中文名稱: |
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英文名稱: |
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其他名稱: |
P-Glycoprotein; Multi Drug Resistance Associated Protein, ABCB1; ATP-binding cassette sub-family B (MDR/TAP), member 1; ABC20; CD243; CD243 antigen; CLCS; Multidrug resistance protein 1; Pglycoprotein 1; p-GP; gp170; Pgp; PGY1. |
產(chǎn)品品牌: |
Pllabs |
產(chǎn)品編號: |
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產(chǎn)品規(guī)格: |
0.1mg/0.2mg |
產(chǎn)品包裝: |
一支包裝(原裝進(jìn)口、進(jìn)口分裝) |
?免 疫 原: |
KLH conjugated synthetic peptide derived from human MDR1(N-terminus) |
***類型: |
Rabbit Polyclonal IgG |
背景介紹: |
malignant cells, typically cells with secretory and excretory functi***. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein h***e also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas. |
應(yīng)用范圍: |
Human, Mouse, Rat(Please decide the specificity by homology) |
更多產(chǎn)品: |
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其他產(chǎn)品: |
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